The primary objective of Core Grants for Vision Research is to provide groups of investigators who have achieved independent National Eye Institute (NEI) funding with additional, shared support to enhance their own and their institution’s capability for conducting vision research. Secondary objectives of this program include facilitating collaborative studies and attracting other scientists to research on the visual system. The center has four modules: Biochemistry/Immunology Module: Expertise in the production, characterization, and utilization of monoclonal antibodies for immunocytochemistry, in situ hybridization of ocular tissues Genotyping/phenotyping module: Mouse and zebrafish PCR genotyping, Electroretinograms for examining ocular phenotype, fluorescent microscopy to detect fluorescent chimeric proteins expressed in the eye of animal models. Morphological Imaging: electron microscopy of visual system, light microscopy and confocal microscopy for analysis visual system, preparation for illustrations and images for manuscripts, and posters. Psychophysics/Physiology Module: development of computer programs for video display, data acquisition and analysis, and hardware calibration for psychophysical experiments.