Transcriptional profiling and other high throughput genomic technologies (e.g. high density SNP genotyping, next generation sequencing) generate large amounts of complex data. The majority of investigators do not possess the skills or expertise in bioinformatics and biostatistics to perform thorough and rigorous data analysis. In addition, research in bioinformatics and biostatistical methods for genomic data continues to develop very rapidly, and even the most statistically savvy life science investigator finds it difficult, if not impossible, to keep up with the field. The Bioinformatics and Biostatistics Core provides support that enables CEEH investigators to incorporate microarray and other high-throughput laboratory assays into their research. The Bioinformatics and Biostatistics Facility Core is a \full-service\” bioinformatics center for the design of studies utilizing high throughput genomic