01 Nov High-dose Influenza Vaccine Study for People Ages 50-64
We are currently recruiting people ages 50 to 64 who have not yet received this season’s (2024-2025) influenza (flu) vaccine to participate in a clinical trial of an investigational flu vaccine. This Phase 3 trial, sponsored by Sanofi, will evaluate how well an investigational high-dose flu vaccine protects against flu infection compared with a licensed standard-dose flu vaccine. The study will only be open to enrollment for a few weeks.
• Participants will receive one injection of either the investigational high-dose flu vaccine or a licensed standard-dose flu vaccine. Participants will not know which of the two vaccines they receive. The high-dose flu vaccine in this study is approved in the US for use in people aged 65 and older.
• The study involves two in-person study visits at our research clinic in downtown Seattle during the first month of the study.
• Participants will be asked to answer questions in a phone app for 8 days to let us know whether they have any reactions after the vaccine.
• Participants will receive a $50 gift card after each in-person visit completed.
• There will be a telephone contact about 6 months after enrollment, and participants will receive a $25 gift card after that call is completed.
• We will provide free parking in our research clinic building’s garage or bus tickets at each visit.
Participant Eligibility
• Healthy adults aged 50 to 64 years
• Able to attend study visits at the Kaiser Permanente Washington Health Research Institute clinic in downtown Seattle
• No medical conditions that affect the immune system and not taking medications that affect the immune system
• No receipt of flu vaccine in the 6 months before enrollment
• There are other conditions that may make you ineligible for this study
Contact
Maya Dunstan
(206) 287-2061
Additional Study Details
Full Study Title
A Phase 3, randomized, modified double-blind, 2-arm study to evaluate the immunogenicity and safety of High-Dose Inactivated Influenza Vaccine (IIV-HD) compared with a standard-dose inactivated influenza vaccine (IIV-SD) in participants 50 through 64 years of age.
Investigator(s)
Lisa Jackson, MD, MPH
Accepts Healthy Volunteers?
Yes
Study Site(s)
Kaiser Permanente Washington Health Research Institute
1730 Minor Ave Suite 1370
Seattle, Washington 98101