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COGIT-2 Trial

COGIT-2 Trial

This study is being conducted to evaluate if cognitive training can improve cognitive performance in participants with memory loss. This study will evaluate the effects of crossword puzzles training and health education for improvement in everyday cognitive performance over an 18-month period.

If you join the study, you will be assigned to 1 of 3 treatment conditions: crossword puzzles 4 times per week, crossword puzzles once per week, or health education. During the study you will need to come to in-person study visits approximately every 3 months for cognitive testing, questionnaires, blood draws, and MRI scans. Participants will be compensated for their time.

Participant Eligibility

To be eligible, you need to be:
-Between the ages of 55-89
-Have been diagnosed with Mild Cognitive Impairment, OR you have concerns about your memory
-English speaking
-Not taking any anti-amyloid medications for Alzheimer’s disease, such as Lequembi (lecanemab) or Kisunla (donanemab)
-Have a relative, friend, or other caregiver who can provide information about your functioning, either in-person or by phone.
-Not currently doing crosswords, Sudoku, or other cognitive training methods on a regular basis

Contact

Hanson Lab
(206) 897-1701

Additional Study Details

Full Study Title
Cognitive Training and Neuroplasticity in Mild Cognitive Impairment

Study ID: 20240282
Start Date: 07/17/2025
End Date: 02/28/2029

Investigator(s)
Dr. Angela Hanson

Accepts Healthy Volunteers?
No

Study Site(s)

University of Washington South Lake Union Diabetes Institute Clinical Research Unit (SLU DICRU)

750 Republican St
Seattle, Washington 98109



Interested?

Use the link below to send a message to the study coordinator, or call the number above to speak directly with a study representative.

I am interested in this research study.

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