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High-dose Influenza Vaccine Study for People Ages 50-64

High-dose Influenza Vaccine Study for People Ages 50-64

We are currently recruiting people ages 50 to 64 who have not yet received this season’s (2024-2025) influenza (flu) vaccine to participate in a clinical trial of an investigational flu vaccine. This Phase 3 trial, sponsored by Sanofi, will evaluate how well an investigational high-dose flu vaccine protects against flu infection compared with a licensed standard-dose flu vaccine. The study will only be open to enrollment for a few weeks.

Participants will receive one injection of either the investigational high-dose flu vaccine or a licensed standard-dose flu vaccine. Participants will not know which of the two vaccines they receive. The high-dose flu vaccine in this study is approved in the US for use in people aged 65 and older.
The study involves two in-person study visits at our research clinic in downtown Seattle during the first month of the study.
Participants will be asked to answer questions in a phone app for 8 days to let us know whether they have any reactions after the vaccine.
Participants will receive a $50 gift card after each in-person visit completed.
There will be a telephone contact about 6 months after enrollment, and participants will receive a $25 gift card after that call is completed.
We will provide free parking in our research clinic building’s garage or bus tickets at each visit.

Participant Eligibility

Healthy adults aged 50 to 64 years
Able to attend study visits at the Kaiser Permanente Washington Health Research Institute clinic in downtown Seattle
No medical conditions that affect the immune system and not taking medications that affect the immune system
No receipt of flu vaccine in the 6 months before enrollment
There are other conditions that may make you ineligible for this study

Contact

Maya Dunstan
(206) 287-2061

Additional Study Details

Full Study Title
A Phase 3, randomized, modified double-blind, 2-arm study to evaluate the immunogenicity and safety of High-Dose Inactivated Influenza Vaccine (IIV-HD) compared with a standard-dose inactivated influenza vaccine (IIV-SD) in participants 50 through 64 years of age.

Study ID: SSU00269394
Start Date: 10/31/2024
End Date: 12/07/2024

Investigator(s)
Lisa Jackson, MD, MPH

Accepts Healthy Volunteers?
Yes

Study Site(s)

Kaiser Permanente Washington Health Research Institute

1730 Minor Ave Suite 1370
Seattle, Washington 98101



Interested?

Use the link below to send a message to the study coordinator, or call the number above to speak directly with a study representative.

I am interested in this research study.

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