alloRESIST | A Study to Evaluate the Safety, Immunologic, and Virologic RESponses of Donor Derived (DD) HIV-Specific T-cells (HST) With Non-escaped Epitope Targeting (NEETs) in HIV-Infected Individuals on Antiretroviral Therapy Following Allogeneic Bone Marrow Transplantation (alloRESIST) | - Children's National Hospital
| NCT04248192 |
ATLANTIC | Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts | - Children's National Hospital
| NCT04691622 |
ATTACK | Phase I Research Study Utilizing Allogeneic Multi Tumor-Associated Antigen-Specific T Lymphocytes to Advance the Care of Patients With High-Risk Solid Tumors | - Children's National Hospital
| NCT05238792 |
BMTCTN1903 | Administration of HIV-specific T Cells to HIV+ Patients Receiving High Dose Chemotherapy Followed by Autologous Stem Cell Rescue - Auto -RESIST. BMTCTN1903 | - Children's National Hospital
| NCT04975698 |
BrainChild-03 | Phase 1 Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors | - Seattle Children's Hospital
| NCT04185038 |
BrainChild-04 | Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors | - Seattle Children's Hospital
| NCT05768880 |
CHEERS | Adoptive Cord Blood ImmunotHerapy Using Expanded Cord Blood T Cells for EBV, CMV, BKV and Adenovirus Reactivation/Infection or ProphylaxiS | - Children's National Hospital
| NCT03594981 |
CRISPR_SCD001 | Transplantation of CRISPRCas9 Corrected Hematopoietic Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease | - UCSF Benioff Children's Hospitals
| NCT04774536 |
EDIT-301 | A Phase 1/2 Study to Evaluate the Safety and Efficacy of a Single Dose of Autologous Clustered Regularly Interspaced Short Palindromic Repeats Gene-edited CD34+ Human Hematopoietic Stem and Progenitor Cells (EDIT-301) in Subjects With Severe Sickle Cell Disease | - UCSF Benioff Children's Hospitals
- Colorado Children's Hospital
| NCT04853576 |
ENLIGHTen-01 | A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+AML | - Seattle Children's Hospital
| NCT051051522 |
HGB 206 | A Phase 1 Study Evaluating Gene Therapy by Transplantation of Autologous CD34+ Stem Cells Transduced Ex Vivo with the LentiGlobin BB305 Lentiviral Vector in Subjects with Severe Sickle Cell Disease | - UCSF Benioff Children's Hospitals
| NCT02140554 |
MeDCaP | Mesenchymal Stromal Cells Delivery Through Cardiopulmonary Bypass in Pediatric Cardiac Surgery (MeDCaP) | - Children's National Hospital
| NCT04236479 |
NATS | Novel Antigens Targeted by ex Vivo Expanded T-Lymphocytes for Prevention or Treatment of Viral Infections Following Hematopoietic Stem Cell Transplantation | - Children's National Hospital
| NCT03180216 |
PLAT-07 | A Pediatric and Young Adult Trial of Genetically Modified T Cells Directed Against CD22 for Relapsed/Refractory Leukemia or Lymphoma | - Children's Hospital Los Angeles
- Seattle Children's Hospital
| NCT04571138 |
PLAT-08 | Pediatric And Young Adult Leukemia Adoptive Therapy (PLAT)-08: A Phase 1 Study Of SC-DARIC33 In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML | - Seattle Children's Hospital
| NCT05105152 |
ReMIND | Phase I REsearch on Multi-antigen T Cell Infusion Against Neuro-oncologic Disease (ReMIND) | - Children's National Hospital
| NCT03652545 |
RESIST | A Phase I Study to Evaluate the Safety, Immunologic, and Virologic RESponses of HIV-Specific T-cells With Non-Escaped Epitope Targeting (HST-NEETs) as a Therapeutic Strategy in HIV-Infected Individuals on Antiretroviral Therapy During Acute And Chronic Infection | - Children's National Hospital
| NCT03485963 |
RESOLVE | Multi-institutional Prospective Phase I Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies | - Children's National Hospital
| NCT02203903 |
REST | Research Study Utilizing Expanded multi-antigen Specific lymphocytes for the treatment of Solid Tumors (REST) | - Children's National Hospital
| NCT02789228 |
STRIvE-01 | Phase I Study of EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults | - Seattle Children's Hospital
| NCT03618381 |
SUSTAIN | Phase I Study Utilizing Tumor Associated Antigen Specific T cells (TAA-T) with PD1 Inhibitor Nivolumab for Relapsed/Refractory Lymphoma | - Children's National Hospital
| NCT03843294 |
TDT | A Phase 1/2, Open-label, Single-arm Study to Assess the Safety, Tolerability, and Efficacy of ST-400 Autologous Hematopoietic Stem Cell Transplant for Treatment of Transfusion-Dependent Beta-thalassemia (TDT) | - UCSF Benioff Children's Hospitals
| NCT03432364 |
TONI | T CELL THERAPY OPPOSING NOVEL COVID-19 INFECTION IN IMMUNOCOMPROMISED PATIENTS | - Children's National Hospital
| NCT05141058 |
UCD19 | Phase I/II Dose Escalation and Preliminary Efficacy of CD19 Directed CAR-T Cells Generated Using the Miltenyi CliniMACs Prodigy System (UCD19 CAR-T) in Pediatric Patients with Relapsed and/or Refractory B-Cell Acute Lymphoblastic Leukemia (B-ALL) and B-Cell Non-Hodgkin Lymphoma (B-NHL) | - Colorado Children's Hospital
| NCT04544592 |
ZUMA-4 | A Phase 1/2 Multi-Center Study Evaluating the Safety and Efficacy of KTE-X19 in Pediatric and Adolescent Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia or Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (ZUMA-4) | - Children's National Hospital
- UCSF Benioff Children's Hospitals
| NCT02625480 |