Request for Applications

ITHS KL2 Multidisciplinary Clinical Research Career Development Program

ITHS › Education & Training › Post-Doctoral Programs › KL2 Multidisciplinary Clinical Research Career Development Program › Request for Applications

Permanent link: https://www.iths.org/?p=28357

ITHS KL2 Multidisciplinary Clinical Research Career Development Program Request for Applications

The ITHS KL2 Multidisciplinary Clinical Research Career Development Program provides the time, funding, mentorship, and training necessary to foster the early career development of clinical and translational researchers. The program is funded by the NIH and welcomes scholars with faculty appointments from all health professions.

KL2 Scholars are appointed for up to three years of support. The program encourages all types of clinical research, including patient-oriented research, translational research, small- and large-scale clinical investigation and trials, epidemiologic and natural history studies, health services research, and health behavior research.

Eligibility Change – Please Read

Please see Eligibility section below for July 2024 update.

Application Period Closed

Key Dates

Application Open
August 12, 2024
Application Deadline
October 7, 2024
Notification of Awards
Mid-December, 2024
Appointment Start Date
March 1, 2025

Info Session: Aug 14th 4-5 (PDT) Register here

KL2 Q&A Sessions

KL2 Q&A Session: July 9^th 1-2pm (PDT)
Registration Link: https://washington.zoom.us/meeting/register/tJcofuGopzkjGtNczyO1OfZMjqzdKV2SOcx7
KL2 Q&A Session: Aug 14^th 4-5pm (PDT)

Registration Link: https://washington.zoom.us/meeting/register/tJEqf-iuqTojGNYBB1xUp9orbcVgV33n3MSY

Career Development Event: How to Write a K-Award Application to Maximize Funding

Go to event page

NIH Diversity Statement

Every facet of the United States scientific research enterprise — from basic laboratory research to clinical and translational research to policy formation — requires superior intellect, creativity, and a wide range of skill sets and viewpoints. NIH’s ability to help ensure that the nation remains a global leader in scientific discovery and innovation is dependent upon a pool of highly talented scientists from diverse backgrounds who will help to further NIH’s mission.

Research shows that diverse teams working together and capitalizing on innovative ideas and distinct perspectives outperform homogenous teams. Scientists and trainees from diverse backgrounds and life experiences bring different perspectives, creativity, and individual enterprise to address complex scientific problems. There are many benefits that flow from a diverse NIH-supported scientific workforce, including: fostering scientific innovation, enhancing global competitiveness, contributing to robust learning environments, improving the quality of the researchers, advancing the likelihood that underserved or health disparity populations participate in, and benefit from health research, and enhancing public trust.

Program Overview

Funding

Eligibility

The KL2 program is open to investigators at the postdoctoral or early career faculty level who plan to conduct, or are conducting, translational research. If you are at the postdoctoral level and do not currently have a faculty appointment, your department support letter will need to indicate that upon acceptance you will have a faculty appointment.

Eligibility Update July 2024: Due to a change in NIH requirements beyond ITHS control, KL2 applications will only be accepted for individuals with an appointment (or expectation of appointment) at one of ITHS partner institutions: University of Washington, Fred Hutchinson Cancer Center, or Seattle Children’s Research Institute.

Faculty at non-partner WWAMI institutions: The KL2 Monthly Seminars & Mentorship will be accessible to our WWAMI scientific community through the KL2 Seminar Fellows Program (additional information and dedicated webpage coming soon). Additionally, ITHS can offer support for development and review of career development award proposals to WWAMI early-stage faculty. The level of support provided will be determined by ITHS capacity, applicant needs, and alignment to ITHS mission and priorities. Please reach out to ithsedu@uw.edu for more information.

Eligibility Requirements

To be considered eligible for the KL2 program, applicants must:

Have an appointment (or expectation of appointment upon acceptance) at one of ITHS partner institutions: University of Washington, Fred Hutchinson Cancer Center, or Seattle Children’s Research Institute.
Be a U.S. citizen or lawful permanent resident. Permanent residents must have a U.S. Permanent Resident Card (form I-551) or other verification of their legal status as a permanent resident at the time of application. Individuals on temporary or student visas are not eligible.
Be at an early stage of their career. Applicants should not have been in a tenure-track Assistant Professor position for more than three years at the time of application.
Have a research or health-professional doctoral degree applicable to clinical research. These degrees include: MD, PhD, DrPH, DO, DDS, DMD, OD, DC, PharmD, ND, PsyD.
Be able to commit a minimum of nine calendar months of full-time professional effort for career development and research activities associated with the program.

Applicants are ineligible for the KL2 Program if they are:

Simultaneously participating in clinical fellowships leading to clinical certification (with some exceptions, see FAQ).
Simultaneously submitting or have pending an application for any other PHS mentored career development awards that duplicate any of the provisions of the KL2 program.
An individual making a mid-career change into clinical research.
A former or current principal investigator on any NIH research project grant or equivalent non-PHS peer reviewed research grants that are over $100,000 direct costs per year, or a project leader on sub-projects of program project (P01) or center grants (P50). Note: this exclusion does not apply to cases of NIH Small Grants (R03) or Exploratory/ Developmental (R21) grants or their equivalents.

Additional Information

The KL2 program cannot support research with a focus on global health or research located outside of the United States.
ITHS strongly encourages applications from from underrepresented scientists and investigators.
Exceptions to the 75% effort requirement may be made for limited specialties (e.g., 50% effort for surgeons and other procedural-based specialties requiring greater clinical effort to maintain clinical skills such as ENT, Orthodontics).

An ITHS membership is required to apply. To become a member, please complete the ITHS Membership Form.

How to Apply

The KL2 Program application consists of standard demographic information, a biosketch from the NIH template, and a detailed and thorough description of your proposed project. In addition, you will need three letters of recommendation.

Key Dates

All materials, including the Letters of Recommendation, must be received by 11:59 p.m. on October 7, 2024.

Application Deadline
October 7, 2024
Notification of Awards
Mid-December, 2024
Appointment Start Date
March 1, 2025

Step 1. Obtain Letters of Recommendation

Letters should be submitted online though the LOR form.

You will need three letters of recommendation:

1) Department, Division, or Institutional Letter of Support
(Note: this letter must address the requirements listed under “Institutional Commitment to Candidate’s Research Career Development” on page K-96 of the NIH Career Development Instructions)
2) Primary Mentor Letter of Support
3) Candidate’s Choice for Letter of Support

Applicants: Please direct people submitting letters for you to the Letter Submission Form as early as possible. All letters of recommendation are due on October 7, 2024.

You can either:

1. Copy the following link, and deliver it any way you’d like (e.g. Craft your own email).
https://www.iths.org/KL2-Letters
– OR –
2. Enter a few details into a form, and we’ll send the link to them for you.

Visit the form

Step 2. Complete the following items prior to accessing the online application

Choose your track.

Applicants will submit under one of the following three tracks of translational science that most accurately describes their proposed project.

Develop	Demonstrate	Disseminate
Therapeutic target identification and/or validation	Phase I or Phase II clinical studies/trials	Epidemiological studies such as case-control, cohort, or meta-analytic studies
Development of novel therapeutics prior to clinical testing	Biomarker identification & validation	Health disparities research
In vitro or cell-based assays	Pharmacokinetics / Pharmacodynamics of novel therapies in humans	Community-based & community participatory research
Research using animal models	Pilot & small proof-of-concept studies in humans	Implementation science

Choose the translational science track in which your proposed project fits best (those unsure of which phase their research falls under should email Christy McKinney, KL2 Program Director, for guidance).

Combine items 4-8 into a single PDF file.

4) NIH Biosketch

28 KBNIH Biosketch Template

37 KBBiosketch Sample

46 KB5) Personal Statement (1 page maximum)

Create a personal statement detailing your interest in the KL2 program and how the program will help further your career as a translational researcher

50 KB6) Research Proposal (2 page maximum, not including references)

Create a hypothesis-based research proposal that includes a mentorship plan

46 KB7) Project Timeline (1 page maximum)

Create a timeline table detailing the progression of your proposed project over three-year KL2 program appointment

173 KB8) Resource Sharing Plan (if required)

Step 3. Complete the online application form

Apply Now or

Submit a LOR

Frequently Asked Questions

FAQs

How is the KL2 program funded?

The NIH KL2 Mentored Clinical Research Scholars Program is funded through NCATS as part of a broad Clinical and Translational Science Awards (CTSA) Initiative.

Permalink

How many funded positions will there be each year?

We hope to select three KL2 scholars each year.

Permalink

Are other federal grants (eg R01 or R21) allowed to support the remaining 25% salary not covered by the KL2 award?

Yes. KL2 scholars are allowed to receive concurrent support from federal sources, as long as the effort dedicated to other grants does not reduce their KL2 effort to below 9 person-months (or .75 FTE) and the support is for a different project with separate goals.

Permalink

How is this award different from NIH individual Career Development Awards (CDA)?

Specific information regarding individual CDAs

Individuals who have already obtained an individual Kaward will not be eligible to apply for our KL2 award.

The KL2 award is an Institutional Mentored Research CDA. It is similar in intent, scope, and funding to individual mentored K awards. All NIH Mentored CDAs have the same general level of effort requirements. However, there are several important differences. The application materials and time to notification are much shorter. A personal interview is required.

A core curriculum will be provided that will develop general scholarship in a breadth of clinical research topics. Intensive clinical research mentorship is also a primary focus of the CTSA KL2 award.

Finally, awards will be determined by a committee comprised of UW, Seattle Children’s, Fred Hutch, and other ITHS partner faculty and affiliated investigators.

Permalink

If a potential scholar is already studying under an existing KL2/K12 award, is he/she eligible for this program?

Early career researchers are normally limited to 6 years of K-support overall. Since the ITHS KL2 program is designed for three years of support, applicants should not have received more than three years of K12 or KL2 support prior to applying. Furthermore, the applicant would need to justify additional mentored research training or training in a team context.

Permalink

Is there a limit on time since completing post-doctoral training, or at what stage should prospective KL2 scholars be?

We have not established explicit limits on time since training. However, this award is best suited for applicants who are early in their professional careers. This award is not meant to serve as support for applicants already established in their field, nor is it meant to aid in a career change. Individuals who have achieved the rank of associate professor are not eligible.

KL2 scholars must hold a doctoral level degree. We are seeking individuals at an early stage of their career, even while they are in sub-specialty training. We expect that KL2 scholars will be postdoctoral level trainees or junior faculty who plan to conduct, or are conducting, clinical and translational research. Some KL2 scholars may be at the tenure-track/assistant professor level when they enter the program, but we hope most KL2 scholars will be at a much earlier stage. We expect that KL2 scholars will become assistant professor or tenure-track clinical research faculty either during or after they progress through the program.

KL2 scholars who achieve promotion to the rank of Associate Professor will have their appointments terminated at the end of the grant year in which this promotion is achieved.

Please see this link for more information:

NIH Career Development Award – Eligible Individuals

Permalink

Can this program be combined with a clinical fellowship?

No.

KL2 funds cannot be used to support clinical fellowship training. However, fellows who have completed the part of their fellowship needed for sub specialty certification are eligible to apply. For example, although a Medical Oncology fellowship may last three to four years, fellows who have completed two years may be eligible to sit for the boards, and are therefore eligible. In general, applicants should be board-eligible for their specialty or subspecialty when they enter the KL2 program.

Permalink

As a KL2 scholar will I be able to conduct research outside of the US and Canada, or focus on Global Health?

The KL2 program cannot support any investigators with a focus on global health and research located outside of the United States. While appointed to the KL2 program, scholars may not participate in any research work or travel outside of the United States and Canada (with the exception of international travel for conference attendance). Conducting research in the United States with foreign samples and data is allowed.

Permalink

Do I have to be a member of a specific Health Science School to apply?

No.

This program strongly encourages applications from members of all UW Health Science Schools. This includes the Schools of Pharmacy, Nursing, Public Health and Community Medicine, Social Work, Dentistry, and Medicine. In addition, the program strongly encourages applications from individuals at ITHS partner and collaborating institutions.

Permalink

Is it possible to see an example of a successful application?

Yes, please email us at ithsedu@uw.edu to request a successful application and include the track to which you will be applying.

Permalink

How do I know which track to apply to?

Take a look at the grid below and see where your project best fits. If it’s still not clear please reach out to ithsedu@uw.edu with a short description of your project and we’ll be happy to assist you.

Develop	Demonstrate	Disseminate
Therapeutic target identification and/or validation	Phase I or Phase II clinical studies/trials	Epidemiological studies such as case-control, cohort, or meta-analytic studies
Development of novel therapeutics prior to clinical testing	Biomarker identification & validation	Health disparities research
In vitro or cell-based assays	Pharmacokinetics / Pharmacodynamics of novel therapies in humans	Community-based & community participatory research
Research using animal models	Pilot & small proof-of-concept studies in humans	Implementation science

Permalink

Contact Us

About You
Name*
First Last
Institution / Organization*
Other Institution / Organization*
Department or Program*
Preferred method(s) of contact*
- Email
- Phone
Email address*
Phone*
Message / Question
Program
Subject*
Message*
Attachments (optional)
Drop files here or

Max. file size: 8 MB.
Phone
This field is for validation purposes and should be left unchanged.

For information regarding this program, contact:

MILU WORKU
Manager of Training Programs
Institute of Translational Health Sciences
850 Republican Street, Box 358051, Seattle, WA 98109
Email / 206.543.0542 / fax 206.616.9250

Print this Page

Page last modified: Oct 8, 2024 @ 8:16 am (PST)

ITHS Tools

Login

Search the Site

Need Help? Have a Question?

Connect with Us

Request for Applications

ITHS KL2 Multidisciplinary Clinical Research Career Development Program Request for Applications

Eligibility Change – Please Read

Application Period Closed

Key Dates

KL2 Q&A Sessions

Career Development Event: How to Write a K-Award Application to Maximize Funding

NIH Diversity Statement

Program Overview

Program Overview

Funding

Funding

Please note:

Eligibility

Eligibility

Eligibility Requirements

Additional Information

How to Apply

How to Apply

Key Dates

Step 1. Obtain Letters of Recommendation

You can either:

Step 2. Complete the following items prior to accessing the online application

Step 3. Complete the online application form

Frequently Asked Questions

FAQs

KL2 Program

Contact Us

Contact Us

About You

Message / Question

ITHS Tools

Login

Search the Site

Need Help? Have a Question?

Connect with Us

Request for Applications

ITHS KL2 Multidisciplinary Clinical Research Career Development Program Request for Applications

Eligibility Change – Please Read

Application Period Closed

Key Dates

KL2 Q&A Sessions

Career Development Event: How to Write a K-Award Application to Maximize Funding

NIH Diversity Statement

Program Overview

Program Overview

Funding

Funding

Please note:

Eligibility

Eligibility

Eligibility Requirements

Additional Information

How to Apply

How to Apply

Key Dates

Step 1. Obtain Letters of Recommendation

You can either:

Step 2. Complete the following items prior to accessing the online application

Step 3. Complete the online application form

Frequently Asked Questions

FAQs

KL2 Program

Contact Us

Contact Us

About You

Message / Question

Email a Link to the KL2 Letter Request Form

Please sign in below to access this form.